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S1 • E1
A thirty-year veteran beat cop and longtime friend of Stone's is shot during an attempted robbery. Stone sets off with a vendetta to get the gunman, blurring the line between professional and personal.
S1 • E2
A would-be Jack The Ripper stalks the city, slashing to death prostitutes. Stone assigns a resistant Keller with protecting a prostitute who has been threatened.
S1 • E3
A businessman who flew in from Los Angeles (the time it takes to fly from L.A. to S.F. is the source of the title) for a convention meets a woman at the convention center and agrees to join her on her houseboat in nearby Sausalito. They get into an argument and he winds up striking her on the head and fleeing. The woman's boyfriend gets home, gets into an argument with her and again bashes her on the head, killing her. The businessman is the prime suspect in the murder because he was seen arriving at and then fleeing the crime scene.
S1 • E4
Stone and Keller contend with an AWOL Vietnam War soldier determined to abduct a five-year-old child.
S1 • E5
Stone and Keller uncover the seedy world of escort services when their suspect is a cultured art collector with a Pygmalion complex who hires escorts determined to create in them his idealized woman.
S1 • E6
Stone is sidelined with a broken ankle, so Keller teams up with hot-headed Inspector Jim Martin to track down a young Mexican suspected of murder. But Martin's prejudice against Mexicans threatens the investigation's success.
S1 • E7
When a parolee whom Stone once coached in the Police Athletic League is accused of murdering another ex-con, Stone, Keller and a caring social worker rally to his defense.
S1 • E8
A city official is murdered in a botched mugging by a gang of three sophisticated criminals unaware of his high profile. The mayor, convinced it was a political assassination, orders Stone and Keller to crack the case.
S1 • E9
Two young women are found murdered in a swinging singles apartment complex. As Stone and Keller investigate, they uncover multiple suspects with a motive to murder the two gold-digging, teasing "takers."
S1 • E10
A band of modern-day Gypsies descends on San Francisco, its aging patriarch unaware that the younger generation has moved on from the traditional flim-flam to million-dollar heists and murder.
S1 • E11
An ex-con college professor takes a bullet to the shoulder when a hit-man murders a blackmailer. But the professor refuses to have the bullet removed, and the hit-man is hot on his trail to recover the incriminating bullet.
S1 • E12
Stone oversteps his authority when he entrusts to a traditional Greek patriarch his ex-con son just released from San Quentin. When the son is implicated in a suspicious fire, Stone and Keller's investigation uncovers ugly family secrets.
S1 • E13
An artist is thrown to his death from his apartment window. Stone and Keller's investigation centers on the daughter of a renowned eccentric poet, who sets to spinning a web of deception to deflect the dogged detectives from her trail.
S1 • E14
Two crusty fishermen at sea stumble upon an illegal alien smuggling ring. The smugglers murder one of the fishermen and pressure the second into silence, stymieing Stone and Keller's investigation.
S1 • E15
In her zeal to capture a serial rapist, a rookie cop flouts Stone's orders, jeopardizing not only Stone and Keller's carefully choreographed stake out but her own life.
S1 • E16
A hit man living a new life with a family in France is lured out of retirement by his former employer, a crime kingpin determined to rub out every witness to a murder he committed.
S1 • E17
A greed-consumed numismatist plots to switch a wealthy collector's gold double-eagle coins with counterfeits, using and abusing his trusting accomplices along the way.
S1 • E18
A war among gambling bosses is being waged. Stone and Keller attempt to locate and protect a vital witness from a hit man who has charmed his way into a lonely schoolteacher's apartment in order to secure a clear shot at his victim.
S1 • E19
A veteran newspaper columnist and longtime friend of Stone's accidentally kills his young, two-timing mistress and then attempts to pin the rap on the young stage actor she was seeing.
S1 • E20
Stone is held hostage by the Cobras street-gang, which demands an exchange for its wounded leader who was captured in a bungled robbery. Keller and Devitt scour the city's seamy underside in their search for their friend and colleague.
S1 • E21
Three young boys open a Pandora's Box when they sneak into an eccentric old man's home, a mysterious house rumored by their parents to contain a million-dollar treasure.
S1 • E22
A homicidal rapist that Stone had put away twelve years earlier is released and begins waging psychological warfare on Stone by stalking his daughter Jeannie.
S1 • E23
A child is killed in a bungled burglary and the perpetrator is set free on a legal technicality. The bereft father is determined to take justice into his own hands, despite Stone's strenuous objections.
S1 • E24
A high-powered Commerce Dept. official is harpooned on a pleasure boat. Stone and Keller sift through the suspects, among whom are a senator, a boat builder and the grieving widow, who is an old friend of Stone's from the Potrero.
S1 • E25
Grand theft cobra venom? That is what seems to be the charge, along with murder, when a robbery attempt of an Asian ship goes wrong and leads to a wild gunfight. A longshoreman is killed and another one is wounded, but steals his assailant's gun, kills him and makes off with a large shipment box supposedly full of cobra venom to be used in research. The wounded man goes into hiding on the docks with the gun and the case, believing he has actually stolen a shipment of much greater value. He meets secretly with a priest and refuses to turn himself in. Meanwhile, Stone and Keller have traced the dead robber to a Mafia unit in San Francisco, and learn on their own that hired guns are coming in to find the longshoreman and finish the theft -- which turns out to be a multimillion-dollar shipment of heroin.
S1 • E26
After three winos are brutally beaten to death, Stone goes undercover as a bum to crack the case.
Detective Lt. Mike Stone
Steve Keller
Inspector Bill Tanner
Inspector Dan Robbins
Bernie
Detective Lee Lessing
Jeannie Stone
Officer Vic Briles
Gerald O'Brien
Dr. Lenny Murchison